POTS Fact Sheet

Primarily women aged 15-50 years, though men can also have POTS

1 to 3 million people in the U.S. are affected by POTS

Common triggers include viral illnesses (e.g., mononucleosis), pregnancy, head injuries, and autoimmune diseases (e.g., lupus, Sjögren's syndrome).

Causes of POTS:
Neuropathic POTS: Nerve damage affecting blood vessels
Hyperadrenergic POTS: Overactive nervous system
Hypovolemic POTS: Low blood volume
Autoimmunity: Growing evidence suggests immune system involvement

80% improvement rate with treatment, though symptoms may persist

Life expectancy is not affected, but quality of life can be impacted by symptoms


Sources:

Cleveland Clinic. (n.d.). Postural Orthostatic Tachycardia Syndrome (POTS). Retrieved from [Cleveland Clinic](https://my.clevelandclinic.org/health/diseases/16560-postural-orthostatic-tachycardia-syndrome-pots)

National Institutes of Health (NIH). Postural Orthostatic Tachycardia Syndrome (POTS). Retrieved from [NIH](https://www.ninds.nih.gov/health-information/disorders/postural-orthostatic-tachycardia-syndrome-pots)